The stuff - OSRS Wiki
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The stuff is purchased from Honest Jimmy's House of Stuff with 50 pieces of eight from the Trouble Brewing minigame on Mos Le'Harmless. Access to the minigame and shop requires completion of the Cabin Fever quest. "The stuff" apparently contains some questionable and/or toxic content, as it has been banned by the Cooks' Guild of Varrock. However, it does not actually cause any negative side effects when used in brewing.
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